Tebanicline benzoate

CAS No.	209326-18-1	Cat. No.	BCP25230
Name	Tebanicline benzoate
Synonyms	Ebanicline benzoate;ABT594 benzoate;
Formula	C16H17ClN2O3	M. Wt	320.77

Description	Tebanicline acts as a partial agonist at neuronal nicotinic acetylcholine receptors, binding to both the α3β4 and the α4β2 subtypes. Tebanicline is an effective synthetic nicotinic (non-opioid) analgesic drug developed by Abbott. It was developed as a less toxic analog of the potent poison dart frog-derived compound epibatidine, which is some 200x stronger than morphine as an analgesic but produces extremely dangerous toxic side effects. Like epibatidine, Tebanicline showed potent analgesic activity against neuropathic pain in both animal and human trials, but with far less toxicity than its parent compound.
Related Products	198283-74-8（Tebanicline tosylate） 209326-19-2（Tebanicline dihydrochloride） 203564-54-9（Tebanicline HCl） 198283-73-7（Tebanicline）
Pathways	Ion Channel/Membrane Transporter Neuro Signaling Pathway
Targets	nAChR

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