ABT-594
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CAS No. | 198283-73-7 | Cat. No. | BCP19181 |
Related Products | 203564-54-9(Tebanicline HCl) 209326-19-2(Tebanicline dihydrochloride) 209326-18-1(Tebanicline benzoate) 198283-74-8(Tebanicline tosylate) | ||
Name | ABT-594 | ||
Synonyms | ABT594;ABT 594;Tebanicline;Ebanicline; | ||
SMILES | |||
Chemical Name | |||
Formula | C9H11ClN2O | M. Wt | 198.652 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Tebanicline, also known as ABT-594 and Ebanicline, a potent synthetic nicotinic (non-opioid) analgesic drug developed by Abbott. It was developed as a less toxic analogue of the potent poison dart frog-derived compound epibatidine, which is some 200x stronger than morphine as an analgesic but produces extremely dangerous toxic side effects. Like epibatidine, tebanicline showed potent analgesic activity against neuropathic pain in both animal and human trials, but with far less toxicity than its parent compound. It acts as a partial agonist at neuronal nicotinic acetylcholine receptors, binding to both the α3β4 and the α4β2 subtypes. |
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