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Tebanicline tosylate Chemical Structure

Tebanicline tosylate

Data Sheet For research use only. Not for human use.
Cat. No. :BCP25229CAS No. :198283-74-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 198283-74-8 Cat. No. BCP25229
Related Products 209326-18-1(Tebanicline benzoate) 209326-19-2(Tebanicline dihydrochloride) 203564-54-9(Tebanicline HCl) 198283-73-7(Tebanicline)
Name Tebanicline tosylate
Synonyms ABT594 tosylate;Tebanicline tosilate;
SMILES CC1=CC=C(C=C1)S(=O)(=O)O.C1CNC1COC2=CN=C(C=C2)Cl
Chemical Name
Formula C16H19ClN2O4S M. Wt 370.85
Purity 98% Storage Store at 4-8°C
Description Tebanicline is a potent synthetic nicotinic (non-opioid) analgesic drug developed by Abbott. It was developed as a less toxic analogue of the potent poison dart frog-derived compound epibatidine, which is some 200x stronger than morphine as an analgesic but produces extremely dangerous toxic side effects. Like epibatidine, tebanicline showed potent analgesic activity against neuropathic pain in both animal and human trials, but with far less toxicity than its parent compound. It acts as a partial agonist at neuronal nicotinic acetylcholine receptors, binding to both the α3β4 and the α4β2 subtypes.
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