Tovorafenib
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1096708-71-2 | Cat. No. | BCP13797 |
| Name | Tovorafenib | ||
| Synonyms | TAK-580; TAK 580; TAK580; BIIB-024;BIIB 024;BIIB024;MLN 2480;MLN-2480;MLN2480; | ||
| SMILES | CC(C1=NC=C(S1)C(=O)NC2=NC=C(C(=C2)C(F)(F)F)Cl)NC(=O)C3=C(C(=NC=N3)N)Cl | ||
| Chemical Name | |||
| Formula | C17H12Cl2F3N7O2S | M. Wt | 506.29 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Tovorafenib is an orally available inhibitor of wild-type and certain mutant forms of A-Raf, B-Raf and C-Raf protein kinases, with potential antineoplastic activity. Upon administration, tovorafenib inhibits Raf-mediated signal transduction pathways, which may lead to an inhibition of tumor cell growth. Raf protein kinases play a key role in the RAF/MEK/ERK signaling pathway, which is often deregulated in human cancers and plays a key role in tumor cell proliferation and survival. | ||
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