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CAS No. | 1226781-44-7 | Cat. No. | BCP08054 |
Name | Omarigliptin | ||
Synonyms | MK3102; MK 3102:MK-3102; | ||
SMILES | CS(=O)(=O)N1C=C2CN(CC2=N1)C3CC(C(OC3)C4=C(C=CC(=C4)F)F)N | ||
Chemical Name | |||
Formula | C17H20F2N4O3S | M. Wt | 398.43 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Omarigliptin (MK-3102) is a competitive, reversible inhibitor of DPP-4 (IC50 = 1.6 nM, Ki = 0.8 nM). It is highly selective over all proteases tested (IC50 > 67 μM), including QPP, FAP, PEP, DPP8, and DPP9 and has weak ion channel activity (IC50 > 30 μM at IKr, Caγ1.2, and Naγ1.5). |
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