Saxagliptin hydrochloride New
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| CAS No. | 709031-78-7 | Cat. No. | BCP21271 |
| Name | Saxagliptin hydrochloride | ||
| Synonyms | Saxagliptin HCl;BMS477118; BMS 477118; BMS-477118; | ||
| SMILES | C1C2CC2N(C1C#N)C(=O)C(C34CC5CC(C3)CC(C5)(C4)O)N.Cl | ||
| Chemical Name | |||
| Formula | C18H26ClN3O2 | M. Wt | 351.87 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Saxagliptin Hydrochloride is the hydrochloride salt form of saxagliptin, an orally bioavailable, potent, selective and competitive, cyanopyrrolidine-based inhibitor of dipeptidyl peptidase 4 (DPP-4), with hypoglycemic activity. Saxagliptin is metabolized into an, although less potent, active mono-hydroxy metabolite.Saxagliptin is a new oral hypoglycemic (anti-diabetic drug) of the new dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Saxagliptin was approved in 2008 for the treatment of type 2 diabetes. Saxagliptin is a competitive DPP4 inhibitor that slows the inactivation of the incretin hormones, thereby increasing their bloodstream concentrations and reducing fasting and postprandial glucose concentrations in a glucose-dependent manner in patients with type 2 diabetes mellitus. . | ||
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