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Ensartinib Chemical Structure

Ensartinib

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP26265CAS No. ：1370651-20-9Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 1370651-20-9 Cat. No. BCP26265
Name Ensartinib
Synonyms X396; X-396; X 396;
SMILES
Chemical Name
Formula C25H25Cl2FN6O3 M. Wt 547.41
Purity 98% Storage Store at 4-8°C
Description Ensartinib, also known as X-396, is an orally available small molecule inhibitor of the receptor tyrosine kinase anaplastic lymphoma kinase (ALK) with potential antineoplastic activity. Upon oral administration, X-396 binds to and inhibits ALK kinase, ALK fusion proteins and ALK point mutation variants. Inhibition of ALK leads to the disruption of ALK-mediated signaling and eventually inhibits tumor cell growth in ALK-expressing tumor cells. ALK belongs to the insulin receptor superfamily and plays an important role in nervous system development.
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