G007-LK New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1380672-07-0 | Cat. No. | BCP11079 |
| Name | G007-LK | ||
| Synonyms | G007LK; G007 LK; | ||
| SMILES | N#CC1=CC=C(C2=NN=C(/C=C/C3=NN=C(C4=NC=C(S(=O)(C)=O)C=C4)N3C5=CC=CC=C5Cl)O2)C=C1 | ||
| Chemical Name | |||
| Formula | C25H16ClN7O3S | M. Wt | 529.96 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | G007-LK is a potent, "rule of 5" compliant and a metabolically stable TNKS1/2 inhibitor. G007-LK displayed high selectivity toward tankyrases 1 and 2 with biochemical IC50 values of 46 nM and 25 nM, respectively, and a cellular IC50 value of 50 nM combined with an excellent pharmacokinetic profile in mice. G007-LK was first discovered by Dr. Stefan Krauss's team. | ||
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