PLX7904
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CAS No. | 1393465-84-3 | Cat. No. | BCP18248 |
Name | PLX7904 | ||
Synonyms | PLX-7904;PLX 7904;PB04; | ||
SMILES | |||
Chemical Name | |||
Formula | C24H22F2N6O3S | M. Wt | 512.53 |
Purity | 98% | Storage | Store at 4-8°C |
Description | PLX7904, also known as PB04, is a potent and selective paradox-breaker RAF inhibitor. PB04 is able to efficiently inhibit activation of ERK1/2 in mutant BRAF melanoma cells but does not hyperactivate ERK1/2 in mutant RAS-expressing cells. |
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