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PPT Chemical Structure

PPT

Data Sheet For research use only. Not for human use.
Cat. No. :BCP41931CAS No. :263717-53-9Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 263717-53-9 Cat. No. BCP41931
Name PPT
Synonyms Propyl pyrazole triol;
SMILES CCCC1=C(N(N=C1C2=CC=C(C=C2)O)C3=CC=C(C=C3)O)C4=CC=C(C=C4)O
Chemical Name
Formula C24H22N2O3 M. Wt 386.44
Purity 98% Storage Store at 4-8°C
Description PPT, also known as Propyl pyrazole triol, is an ERα selective agonist with a 410-fold relative binding affinity for ERα (49%) versus ERβ (0.12%) and therefore activates gene transcription only through ERα. PPT significantly decreased infarct size in an in vivo rabbit model of ischemia-reperfusion injury. PPT also exerts anti-diabetic effects in mouse models.
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