BML 190
Data Sheet
For research use only. Not for human use.
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| CAS No. | 2854-32-2 | Cat. No. | BCP02700 |
| Name | BML 190 | ||
| Synonyms | BML-190;BML190; LM-4131; LM4131; LM 4131; IMMA; Indomethacin Morpholinylamide; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C23H23ClN2O4 | M. Wt | 426.89 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | BML-190 has 50-fold selectivity for CB2 receptors over CB1 receptors. In HEK-293 cells stably expressing the human CB2 receptor, BML-190 potentiates the forskolin-stimulated accumulation of cAMP. BML-190 reduces the basal levels of inositol phosphate production in cells expressing the CB2 receptor. 10 μM of BML-190 decreases inositol phosphates accumulation by 38%.BML-190 is an aminoalkylindole. BML-190 is found to yield at least 15 metabolic products.BML-190 diminishes LPS-induced NO and IL-6 production in a concentration-dependent manner. BML-190 also inhibits LPS-induced PGE2 production and COX-2 induction. | ||
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