Netupitant
Data Sheet
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| CAS No. | 290297-26-6 | Cat. No. | BCP08751 |
| Name | Netupitant | ||
| Synonyms | Ro 67-3189; Ro-67-3189; Ro67-3189; Ro-673189000;CID6451149; CID 6451149; CID-6451149; | ||
| SMILES | CN1CCN(C2=CC(C3=C(C)C=CC=C3)=C(N(C)C(C(C4=CC(C(F)(F)F)=CC(C(F)(F)F)=C4)(C)C)=O)C=N2)CC1 | ||
| Chemical Name | |||
| Formula | C30H32F6N4O | M. Wt | 578.59 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Netupitant is a selective neurokinin 1 (NK1) receptor antagonist with potential antiemetic activity. Netupitant competitively binds to and blocks the activity of the human substance P/NK1 receptors in the central nervous system (CNS), thereby inhibiting NK1-receptor binding of the endogenous tachykinin neuropeptide substance P (SP), which may result in the prevention of chemotherapy-induced nausea and vomiting (CINV). | ||
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