BAY 59-3074
Data Sheet
For research use only. Not for human use.
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| CAS No. | 406205-74-1 | Cat. No. | BCP18330 |
| Name | BAY 59-3074 | ||
| Synonyms | BAY59 3074;BAY593074; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C18H13F6NO4S | M. Wt | 453.36 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | In vitro: analgesic, antihyperalgesic, and antiallodynic properties in rat models of acute and chronic pain. The reference concentration is 10 μM. In vivo: administration of BAY 59-3074 (ED50 value: 0.41 mg/kg).Orally active CB1 agonist in vivo. BAY 59-3074 (0.3-3 mg/kg, p.o.) induce antihyperalgesic and antiallodynic effects against thermal or mechanical stimuli in rat models of chronic neuropathic. Antiallodynic efficacy of BAY 59-3074 (1 mg/kg, p.o.) in the spared nerve injury model was maintained after 2 weeks of daily administration. However, tolerance developed rapidly (within 5 days) for cannabinoid-related side effect. BAY 59-3074 have analgesic, antihyperalgesic, and antiallodynic properties in rat models of acute and chronic pain. | ||
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