Nimesulide

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP10076CAS No. ：51803-78-2Purity：98%

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CAS No.	51803-78-2	Cat. No.	BCP10076
Name	Nimesulide
Synonyms	Flogovital;Aulin;R805;R-805;R 805;
SMILES
Chemical Name
Formula	C13H12N2O5S	M. Wt	308.31
Purity	98%	Storage	Store at 4-8°C
Description	Nimesulide is a selective COX-2 inhibitor used in a variety of inflammatory, pain and fever states. After healthy volunteers received oral nimesulide 100 mg in tablet, granule or suspension form the drug was rapidly and extensively absorbed. Mean peak concentrations (Cmax) of 2.86 to 6.50 mg/L were achieved within 1.22 to 2.75 hours of administration . Nimesulide is an NSAID which exerts its analgesic, anti-inflammatory and antipyretic activities thanks to unique chemical and pharmacokinetic characteristics, and to a multifactorial mechanism of action, which goes beyond its preferential inhibitory activity on the COX-2 enzyme. Nimesulide was found to be at least as effective, or superior, to placebo and other NSAIDs, with a particularly fast onset of analgesic action. nimesulide remains an effective and safe therapeutic choice for the treatment of various painful inflammatory conditions, with a rapid onset of analgesic activity and an overall positive benefit/risk profile .