Sitagliptin phosphate New
* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
CAS No. | 654671-78-0 | Cat. No. | BCP04564 |
Name | Sitagliptin phosphate | ||
Synonyms | MK-0431 phosphate;MK 0431 phosphate;MK0431 phosphate; | ||
SMILES | |||
Chemical Name | |||
Formula | C16H15F6N5O.H3PO4 | M. Wt | 505.31 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Sitagliptin phosphate is a potent inhibitor of DPP4 in Caco-2 cell extracts.As an orally active agent, Sitagliptin phosphate exhibits a potent inhibitory effect on DPP-4 with IC50 of 19 nM from Caco-2 cell extracts. MK0431 reduces in vitro migration of isolated splenic CD4 T-cells through a pathway involving cAMP/PKA/Rac1 activation.A recent study demonstrates that sitagliptin exerts a novel, direct action in order to stimulate GLP-1 secretion by the intestinal L cell through a DPP-4-independent, protein kinase A- and MEK-ERK1/2-dependent pathway. It therefore reduces the effect of autoimmunity on graft survival. |
Recommend Products
More >-
Gemigliptin
Cat. No.:BCP40330
No.:911637-19-9
Product Details -
Talabostat isomer mesylate
Cat. No.:BCP38291
No.:TIM
Product Details -
-
Talabostat
Cat. No.:BCP32163
No.:149682-77-9
Product Details -
UAMC00039 dihydrochloride
Cat. No.:BCP20664
No.:697797-51-6
Product Details -
-
Dutogliptin
Cat. No.:BCP24061
No.:852329-66-9
Product Details -
Gosogliptin
Cat. No.:BCP24056
No.:869490-23-3
Product Details -
Retagliptin Hydrochloride
Cat. No.:BCP23802
No.:1174038-86-8
Product Details -
Retagliptin
Cat. No.:BCP23796
No.:1174122-54-3
Product Details -
Retagliptin Phosphate
Cat. No.:BCP23795
No.:1256756-88-3
Product Details -
(2R)-Vildagliptin
Cat. No.:BCP13427
No.:1036959-27-9
Product Details -
Saxagliptin hydrochloride hydrate
Cat. No.:BCP12740
No.:1370409-28-1
Product Details -
Teneligliptin hydrobromide
Cat. No.:BCP12262
No.:906093-29-6
Product Details -
Anagliptin
Cat. No.:BCP28124
No.:739366-20-2
Product Details -
Teneligliptin
Cat. No.:BCP09093
No.:760937-92-6
Product Details -
NVP DPP 728 dihydrochloride
Cat. No.:BCP08983
No.:247016-69-9
Product Details -
Alogliptin benzoate
Cat. No.:BCP08885
No.:850649-62-6
Product Details -
Talabostat mesylate
Cat. No.:BCP04652
No.:150080-09-4
Product Details -
Saxagliptin hydrochloride
Cat. No.:BCP21271
No.:709031-78-7
Product Details
Tags:Sitagliptin phosphate supplier,Sitagliptin phosphate purchase,Sitagliptin phosphate manufacturer,Sitagliptin phosphate distributor,Sitagliptin phosphate cost,Sitagliptin phosphate buy,Sitagliptin phosphate for sale