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JW-55 Chemical Structure

JW-55

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP08451CAS No. ：664993-53-7Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 664993-53-7 Cat. No. BCP08451
Name JW-55
Synonyms JW55;JW 55;
SMILES
Chemical Name
Formula C25H26N2O5 M. Wt 434.48
Purity 98% Storage Store at 4-8°C
Description JW 55 efficacy causes stabilization of Axin2 and it increases degradation of β-catenin signaling pathway. JW 55 also decreases canonical Wnt signaling in SW480 and HCT-15 colon carcinoma cell lines. Wnt3a-induced HEK293 cells containing a transiently transfected ST-Luc (SuperTop-luciferase) reporter showed inhibition by JW55 with an IC50 value of 470 nM.
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