Arglabin New

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP09930CAS No. ：84692-91-1Purity：98%

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CAS No.	84692-91-1	Cat. No.	BCP09930
Name	Arglabin
Synonyms	(+)-Arglabin;
SMILES
Chemical Name
Formula	C15H18O	M. Wt	246.3
Purity	98%	Storage	Store at 4-8°C
Description	in vitro: Arglabin-stimulated macrophages displayed a strong cytotoxic activity and the lowest doses (1.25 micrograms/mL and 0.125 micrograms/mL) induced a significant stimulation of cell mitochondrial metabolism, which correlated with [3H]TdR uptake by J774.1 cells under the same experimental conditions. Arglabin triggered the production of the three cytokines from J774-1 cells. However, the pattern of cytokine secretion differed to some extent, according to the methodology used for cytokine measurement: either traditional bioassay or specific immunoassay (ELISA). Arglabin exhibits antiexudative and antiproliferative properties on the models of acute aseptic inflammation caused by formalin, carrageenan, and histamine, and on the model of proliferative inflammation accompanying cotton-pellet granuloma. Arglabin is able to reduce the proportion of AML stem cells (CD34+CD38-) in primary AML cells.