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CAS No. | 868273-06-7 | Cat. No. | BCP08021 |
Name | Org 27569 | ||
Synonyms | Org27569; Org-27569; | ||
SMILES | CCC1=C(NC2=C1C=C(C=C2)Cl)C(=O)NCCC3=CC=C(C=C3)N4CCCCC4 | ||
Chemical Name | |||
Formula | C24H28ClN3O | M. Wt | 409.95 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Org 27569 is a potent CB1 receptor allosteric modulator (pEC50 = 8.24). Significantly increases binding of the CB1 agonist [3H]CP 55.940 (pKb = 5.67) and decreases binding of the CB1 inverse agonist [3H]SR 141716A (pKb = 5.95). Inhibits CB1 receptor antagonist efficacy in vitro (pKb = 7.57). |
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