CTOPA New
Data Sheet
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| CAS No. | 103429-31-8 | Cat. No. | BCP24191 |
| Name | CTOPA | ||
| Synonyms | CTOP;Ctop-NH2;D-PHE-CYS-TYR-D-TRP-ORN-THR-PEN-THR-NH2; | ||
| SMILES | CC(C1C(=O)NC(C(SSCC(C(=O)NC(C(=O)NC(C(=O)NC(C(=O)N1)CCCN)CC2=CNC3=CC=CC=C32)CC4=CC=C(C=C4)O)NC(=O)C(CC5=CC=CC=C5)N)(C)C)C(=O)NC(C(C)O)C(=O)N)O | ||
| Chemical Name | |||
| Formula | C50H67N11O11S2 | M. Wt | 1062.26 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | CTOP is a potent and selective μ opioid receptor antagonist (Ki values are 0.96 and >10,000 nM for μ and δ receptors respectively). Causes behavioral effects on central administration in vivo. Also increases K+ currents in rat locus ceruleus neurons in vitro via a μ receptor independent mechanism. | ||
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