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Gabazine Chemical Structure

Gabazine

Data Sheet For research use only. Not for human use.
Cat. No. :BCP33110CAS No. :105538-73-6Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 105538-73-6 Cat. No. BCP33110
Name Gabazine
Synonyms SR95531; SR 95531; SR-95531;
SMILES COC1=CC=C(C=C1)C2=NN(C(=N)C=C2)CCCC(=O)O
Chemical Name
Formula C15H17N3O3 M. Wt 287.31
Purity 98% Storage Store at 4-8°C
Description Gabazine is a selective, competitive GABAA receptor antagonist. Displaces [3H]-GABA from rat brain membranes with a Ki of 150 nM. Unlike bicuculline, selectively antagonizes GABA-induced Cl- currents with little action on pentobarbitone-induced currents. Also acts as a low affinity glycine receptor antagonist.
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