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CAS No. | 105538-73-6 | Cat. No. | BCP33110 |
Name | Gabazine | ||
Synonyms | SR95531; SR 95531; SR-95531; | ||
SMILES | COC1=CC=C(C=C1)C2=NN(C(=N)C=C2)CCCC(=O)O | ||
Chemical Name | |||
Formula | C15H17N3O3 | M. Wt | 287.31 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Gabazine is a selective, competitive GABAA receptor antagonist. Displaces [3H]-GABA from rat brain membranes with a Ki of 150 nM. Unlike bicuculline, selectively antagonizes GABA-induced Cl- currents with little action on pentobarbitone-induced currents. Also acts as a low affinity glycine receptor antagonist. |
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