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MK6096 Chemical Structure

MK6096

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP07891CAS No. ：1088991-73-4Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 1088991-73-4 Cat. No. BCP07891
Name MK6096
Synonyms MK 6096; MK-6096;
SMILES
Chemical Name
Formula C24H25FN4O2 M. Wt 420.48
Purity 98% Storage Store at 4-8°C
Description MK-6096 is an orally bioavailable potent and selective reversible antagonist of Orexin 1 Receptor (OX(1)R) and Orexin 2 Receptor (OX(2)R). In radioligand binding and functional cell based assays MK-6096 demonstrated potent binding and antagonism of both human OX(1)R and OX(2)R (<3 nM in binding, 11 nM in FLIPR), with no significant off-target activities against a panel of >170 receptors and enzymes. MK-6096 occupies 90% of human OX(2)Rs expressed in transgenic rats at a plasma concentration of 1
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