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CAS No. | 1164096-85-8 | Cat. No. | BCP49539 |
Name | Onilcamotide | ||
Synonyms | RV001; | ||
SMILES | |||
Chemical Name | |||
Formula | C96H177N39O24S | M. Wt | 2293.78 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Onilcamotide is a cancer vaccine composed of an immunogenic peptide derived from the Ras homolog family member C (RhoC; Rho-related GTP-binding protein RhoC) that is emulsified in the immunoadjuvant montanide ISA-51, with potential immunomodulating and antineoplastic activities. Upon subcutaneous administration, onilcamotide may stimulate the host immune system to mount a humoral and cytotoxic T-lymphocyte (CTL) response against tumor cells expressing RhoC, which results in tumor cell lysis. RhoC, a tumor-associated antigen (TAA) that is overexpressed in a variety of tumor cell types, is associated with increased metastatic potential. |
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