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CAS No. | 1350653-20-1 | Cat. No. | BCP18886 |
Name | Vericiguat | ||
Synonyms | BAY1021189; BAY 1021189; BAY-1021189; BAY10-21189; BAY-10-21189; BAY 10-21189; | ||
SMILES | O=C(OC)NC1=C(N)N=C(C2=NN(CC3=CC=CC=C3F)C4=NC=C(F)C=C42)N=C1N | ||
Chemical Name | |||
Formula | C19H16F2N8O2 | M. Wt | 426.38 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Vericiguat, also known as BAY1021189 or BAY10-21189, is a potent and orally active sGC stimulator (Soluble Guanylate Cyclase Stimulator). Direct stimulation of soluble guanylate cyclase (sGC) is emerging as a potential new approach for the treatment of renal disorders. sGC catalyzes the formation of cyclic guanosine monophosphate (cGMP), deficiency of which is implicated in the pathogenesis of chronic kidney disease (CKD). |
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