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CAS No. | 1378535-08-0 | Cat. No. | BCP49203 |
Name | Alintegimod | ||
Synonyms | 7HP349;7HP 349;7HP-349; | ||
SMILES | C1=CSC(=C1)CN(CC2=CC=CS2)C(=O)OCCOCCOCCOC(=O)N(CC3=CC=CS3)CC4=CC=CS4 | ||
Chemical Name | |||
Formula | C28H32N2O6S4 | M. Wt | 620.81 |
Purity | 98% | Storage | Store at 4-8°C |
Description | 7HP349 is an oral therapy intended for use in combination with immunotherapy in order to improve the effectiveness of potentially any immunotherapeutic immune checkpoint inhibitors and infectious disease vaccines through a unique mechanism of action. It works as an allosteric activator of the integrins VLA-4 and LFA-1 which are essential elements that underlie rate-limiting steps in lymphocyte recruitment, extravascular trafficking, T cell activation and effector functions. |
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