CGP 52411 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 145915-58-8 | Cat. No. | BCP27630 |
| Name | CGP 52411 | ||
| Synonyms | CGP52411;CGP-52411;DAPH; | ||
| SMILES | C1=CC=C(C=C1)NC2=C(C=C3C(=C2)C(=O)NC3=O)NC4=CC=CC=C4 | ||
| Chemical Name | |||
| Formula | C20H15N3O2 | M. Wt | 329.36 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | CGP 52411, also called DAPH, inhibits and reverses the formation of Aβ42 fibers (β-sheet content of aggregated β-amyloid (1-42): IC50 = 4.5 µM) in neurons associated with Alzheimer's disease. And it is also a selective inhibitor of the epidermal growth factor receptor (EGFR) (IC50 = 0.3 μM in vitro). | ||
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