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Indisulam Chemical Structure

Indisulam

Data Sheet For research use only. Not for human use.
Cat. No. :BCP06110CAS No. :165668-41-7Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 165668-41-7 Cat. No. BCP06110
Name Indisulam
Synonyms E7070; E 7070; E-7070; ER35744; ER 35744; ER-35744; D04522;
SMILES
Chemical Name
Formula C14H12ClN3O4S2 M. Wt 385.85
Purity 98% Storage Store at 4-8°C
Description Indisulam, also known as E7070, is a carbonic anhydrase inhbitor, is also a novel synthetic sulfonamide that targets the G1 phase of the cell cycle. The potential antitumor activity of Indisulam was discovered through optimization of the structure-activity relationships of a series of sulfonamide structures. Indisulam causes a blockade in the G1/S transition through inhibition of the activation of both cyclin-dependent kinase 2 and cyclin E. Preclinical studies with Indisulam showed activity in multiple tumor types, most prominently in colon and lung cancer.
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