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CAS No. | 1699720-89-2 | Cat. No. | BCP25916 |
Name | ML753286 | ||
Synonyms | ML-753286; ML 753286; | ||
SMILES | CC1C(=O)N2C(CC3=C(C2CC(C)C)NC4=C3C=CC(=C4)OC)C(=O)N1 | ||
Chemical Name | |||
Formula | C20H25N3O3 | M. Wt | 355.44 |
Purity | 98% | Storage | Store at 4-8°C |
Description | ML753286 is an orally active and selective BCRP (Breast cancer resistance protein) inhibitor with an IC50 of 0.6 μM. ML753286 has high permeability and low to medium clearance in rodent and human liver S9 fractions, and is stable in plasma cross species. |
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