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Acotiamide Chemical Structure

Acotiamide

Data Sheet For research use only. Not for human use.
Cat. No. :BCP21087CAS No. :185106-16-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 185106-16-5 Cat. No. BCP21087
Name Acotiamide
Synonyms YM443; YM-443; YM 443; Z338; Z-338; Z 338;
SMILES CC(C)N(CCNC(=O)C1=CSC(=N1)NC(=O)C2=CC(=C(C=C2O)OC)OC)C(C)C
Chemical Name
Formula C21H30N4O5S M. Wt 450.55
Purity 98% Storage Store at 4-8°C
Description Acotiamide is a prokinetic agent with gastrointestinal (GI) motility-enhancing activity. Although the exact mechanism by which acotiamide exerts its effect has yet to be fully elucidated, this agent appears to inhibit acetylcholinesterase (AchE), an enzyme responsible for the breakdown of acetylcholine (Ach). Increased Ach concentrations lead to an improvement of gastric emptying and GI motility and eventually to a reduction of dyspepsia symptoms.
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