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CAS No. | 2055599-51-2 | Cat. No. | BCP32720 |
Name | NTP42 | ||
Synonyms | NTP 42;NTP-42; | ||
SMILES | CC(C)(C)NC(=O)NS(=O)(=O)C1=C(C=CC(=C1)C#N)OC2=CC=CC(=C2)C3=CC=C(C=C3)OC(F)F | ||
Chemical Name | |||
Formula | C25H23F2N3O5S | M. Wt | 515.53 |
Purity | 98% | Storage | Store at 4-8°C |
Description | NTP42 is a thromboxane A2 (TXA2) receptor antagonist with an IC50 of 3.278 nM for antagonizing T prostanoid receptor (TP)- mediated [Ca2+] mobilization following stimulation of cells with the alternative TP agonist U46609. NTP42 can be used for the treatment of pulmonary arterial hypertension (PAH). |
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