Dalcetrapib
Data Sheet
For research use only. Not for human use.
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| CAS No. | 211513-37-0 | Cat. No. | BCP01932 |
| Name | Dalcetrapib | ||
| Synonyms | JTT-705;RO-4607381;JTT705;JTT 705;RO 4607381;RO4607381; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C23H35NO2S | M. Wt | 389.59 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Dalcetrapib modulates CETP activity. Dalcetrapib induces a conformational change in CETP, when added to human plasma. CETP-induced pre-β-HDL formation in human plasma is unchanged by Dalcetrapib ≤3 μM and increased at 10 μM. Dalcetrapib statistically and significantly increases pre-β-HDL formation.Dalcetrapib achieves 50% inhibition of CETP activity in human plasma at a concentration of 9 μM. [2] Dalcetrapib inhibits the CETP activity of media in HepG2 in a dose-dependent manner. | ||
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