HPK1-IN-22 New
Data Sheet
For research use only. Not for human use.
| Size | Price | Stock | Quotation Inquiry |
|---|---|---|---|
| 10.00 mg | Get quote | In-stock | Quotation Inquiry |
| 25.00 mg | Get quote | In-stock | Quotation Inquiry |
| 100.00 mg | Get quote | In-stock | Quotation Inquiry |
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 2380300-79-6 | Cat. No. | BCP35846 |
| Name | HPK1-IN-22 | ||
| Synonyms | ZYF0033; | ||
| SMILES | CC(O)(C)C#CC1=CC=CC(COC2=CC(C3=CN=C(C4CCN(C)CC4)S3)=CN=C2N)=C1 | ||
| Chemical Name | |||
| Formula | C26H30N4O2S | M. Wt | 462.61 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | HPK1-IN-22 is a hematopoietic progenitor kinase 1 (HPK1) inhibitor with an IC50 less than 10 nM based on the phosphorylation inhibition of MBP protein. HPK1-IN-22 decreases the phosphorylation of SLP76 (serine 376). HPK1-IN-22 promotes anticancer immune responses. HPK1-IN-22 inhibits tumor growth and caused increases intratumoral infiltration of DCs, NK cells, and CD107a+CD8+ T cells but decreased infiltration of regulatory T cells, PD-1+CD8+ T cells, TIM-3+CD8+ T cells, and LAG3+CD8+ T cells in the 4T-1 syngeneic mouse model. | ||
Recommend Products
More >
-
4-(6-Methacryloyloxyhexyloxy)phenol
Cat. No.：BCP49675
No.：142627-92-7
Product Details -
2-Ethylisothiazolidine 1,1-dioxide
Cat. No.：BCP49674
No.：73343-04-1
Product Details -
5-Chloro-2-methyl-3-nitrobenzoic acid
Cat. No.：BCP49668
No.：154257-81-5
Product Details -
4-Ethynylaniline
Cat. No.：BCP49667
No.：14235-81-5
Product Details -
2,5-Dichloro-2,5-dimethylhexane
Cat. No.：BCP49666
No.：6223-78-5
Product Details -
Ethyl 3-Methylpyrazole-4-carboxylate
Cat. No.：BCP49665
No.：85290-78-4
Product Details -
Methyldiphenylphosphine
Cat. No.：BCP49664
No.：1486-28-8
Product Details -
3-Methylcyclopent-2-en-1-one
Cat. No.：BCP49662
No.：2758-18-1
Product Details -
Methyl 2-ethyl-3-oxopentanoate
Cat. No.：BCP49661
No.：32493-32-6
Product Details -
(1R,2R)-1,2-Bis(2-hydroxyphenyl)ethylenediamine
Cat. No.：BCP49655
No.：870991-70-1
Product Details -
Tetrachlorocyclopropene
Cat. No.：BCP49645
No.：6262-42-6
Product Details -
3,4-(Methylenedioxy)butyrophenone
Cat. No.：BCP49637
No.：63740-97-6
Product Details -
Ethyl cis-4,5-dimethyl-3-oxo-5-(trifluoromethyl)tetrahydrofuran-2-carboxylate
Cat. No.：BCP49634
No.：2649469-21-4
Product Details -
5-(5-(1-Cyclopropyl-5,6-difluoro-1H-benzo[d]imidazol-2-yl)pyridin-3-yl)-1,3-dimethoxy-8-methyl-5H-dibenzo[b,d]thiophen-5-ium trifluoromethanesulfonate
Cat. No.：BCP49633
No.：2786716-47-8
Product Details -
3,5-Difluoronitrobenzene
Cat. No.：BCP49632
No.：2265-94-3
Product Details -
1,3,6-Trichloro-2,7-naphthyridine
Cat. No.：BCP49626
No.：2578392-33-1
Product Details -
Tert-butyl (4-fluoro-3-formylpyridin-2-yl)carbamate
Cat. No.：BCP49625
No.：1446091-81-1
Product Details -
(R)-1-(3-nitro-5-(trifluoromethyl)phenyl)ethan-1-amine hydrochloride
Cat. No.：BCP49624
No.：2230840-47-6
Product Details -
N'-(4-(diethylamino)-2-hydroxybenzylidene)isonicotinohydrazide
Cat. No.：BCP49622
No.：917777-63-0
Product Details -
2-Piperazin-1-yl-5-(trifluoromethyl)pyrimidine
Cat. No.：BCP40642
No.：745066-18-6
Product Details
Tags:HPK1-IN-22 supplier,HPK1-IN-22 purchase,HPK1-IN-22 manufacturer,HPK1-IN-22 distributor,HPK1-IN-22 cost,HPK1-IN-22 buy,HPK1-IN-22 for sale