Rotigaptide New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 355151-12-1 | Cat. No. | BCP24086 |
| Name | Rotigaptide | ||
| Synonyms | GAP-486; ZP-123; GAP486; ZP123; GAP 486; ZP 123; | ||
| SMILES | CC(C(=O)NCC(=O)N)NC(=O)CNC(=O)C1CC(CN1C(=O)C2CCCN2C(=O)C(CC3=CC=C(C=C3)O)NC(=O)C)O | ||
| Chemical Name | |||
| Formula | C28H39N7O9 | M. Wt | 617.65 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Rotigaptide is a novel and specific modulator of connexin 43 (Cx43). Rotigaptide prevents the uncoupling of Cx43-mediated gap junction communication and normalizes cell-to-cell communication during acute metabolic stress. Rotigaptide is a potent antiarrhythmic peptide (AAP) with improved stability and has the potential for the investigation of cardiac arrhythmias-specifically atrial fibrillation. | ||
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