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Dextromethadone Chemical Structure

Dextromethadone

Data Sheet For research use only. Not for human use.
Cat. No. :BCP49227CAS No. :5653-80-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 5653-80-5 Cat. No. BCP49227
Name Dextromethadone
Synonyms Esmethadone;S-Methadone;
SMILES CCC(=O)C(CC(C)N(C)C)(C1=CC=CC=C1)C2=CC=CC=C2
Chemical Name
Formula C21H27NO M. Wt 309.4
Purity 98% Storage Store at 4-8°C
Description Dextromethadone is a 6-(dimethylamino)-4,4-diphenylheptan-3-one that has (S)-configuration. It is the less active enantiomer of methadone and has very little activity on opioid receptors and mainly responsible for the inhibition of hERG K+ channels and thus for cardiac toxicity. The drug is currently under clinical development for the treatment of major depressive disorder. It has a role as a NMDA receptor antagonist and an opioid analgesic. It is an enantiomer of a levomethadone.
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