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Oligomycin A Chemical Structure

Oligomycin A

Data Sheet For research use only. Not for human use.
Cat. No. :BCP14686CAS No. :579-13-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 579-13-5 Cat. No. BCP14686
Name Oligomycin A
Synonyms MCH 32; MCH 32; MCH 32;
SMILES
Chemical Name
Formula C45H74O11 M. Wt 791.06
Purity 98% Storage Store at 4-8°C
Description Oligomycin A, also known as MCH 32, is an inhibitor of ATP synthase. Oligomycin A inhibits ATP synthase by blocking its proton channel (Fo subunit), which is necessary for oxidative phosphorylation of ADP to ATP (energy production). The inhibition of ATP synthesis by oligomycin A will significantly reduce electron flow through the electron transport chain; however, electron flow is not stopped completely due to a process known as proton leak or mitochondrial uncoupling. This process is due to facilitated diffusion of protons into the mitochondrial matrix through an uncoupling protein such as thermogenin, or UCP1.
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