Moxonidine
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CAS No. | 75438-57-2 | Cat. No. | BCP23003 |
Name | Moxonidine | ||
Synonyms | BDF5895;BDF-5895;BDF 5895;BE 5895; BE-5895; BE5895; | ||
SMILES | CC1=NC(OC)=C(NC2=NCCN2)C(Cl)=N1 | ||
Chemical Name | |||
Formula | C9H12ClN5O | M. Wt | 241.68 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Moxonidine is a centrally acting antihypertensive drug that is selective agonist at the imidazoline receptor subtype 1 (I1). This receptor subtype is found in both the rostral ventro-lateral pressor and ventromedial depressor areas of the medulla oblongata. Moxonidine therefore causes a decrease in sympathetic nervous system activity and a decrease in blood pressure. Moxonidine may also promote sodium excretion, improve insulin resistance and glucose tolerance and protect against hypertensive target organ damage, such as kidney disease and cardiac hypertrophy. |
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