Amantadine
Data Sheet
For research use only. Not for human use.
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| CAS No. | 768-94-5 | Cat. No. | BCP09869 |
| Name | Amantadine | ||
| Synonyms | ADS-5102, EXP 105-1; EXP-105-1; GP 38026; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C10H17N | M. Wt | 151.25 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Amantadine is a drug that has U.S. Food and Drug Administration approval for use both as an antiviral and an anti-parkinsonian drug. Amantadine is a weak antagonist of the NMDA-type glutamate receptor, increases dopamine release, and blocks dopamine reuptake. Amantadine probably does not inhibit MAO enzyme. Moreover, the mechanism of its antiparkinsonian effect is poorly understood.[citation needed] The drug has many effects in the brain, including release of dopamine and norepinephrine from nerve endings. It appears to be a weak NMDA receptor antagonist as well as an anticholinergic, specifically a nicotinic alpha-7 antagonist like the similar pharmaceutical memantine. | ||
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