Sertraline
Data Sheet
For research use only. Not for human use.
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| CAS No. | 79617-96-2 | Cat. No. | BCP26219 |
| Name | Sertraline | ||
| Synonyms | Sealdin; Adjuvin; Atruline; CP 51,974-1; Cp-51,974-1; CP 51,974; CP51,974; CP-51,974; Gladem; Tatig; Tresleen; Zoloft; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C17H17Cl2N | M. Wt | 306.23 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Sertraline is a selective serotonin uptake inhibitor that is used in the treatment of depression. Sertraline is primarily a serotonin reuptake inhibitor (SRI) with a binding affinity towards the serotonin transporter of Ki=2.8 nM or in that range. Sertraline is also a dopamine reuptake inhibitor, (<50 nmol/L). However, this is not considered a tight binding, and this action is only 10% of its potency as a monoamine reuptake inhibitor. It is a σ1 receptor agonist with 5% of its SRI potency, and an α1-adrenoreceptor antagonist with 1–10% of its SRI potency. | ||
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