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CAS No. | 8068-37-9 | Cat. No. | BCP15947 |
Name | Colistimethate Sodium | ||
Synonyms | Colistimethate;Colistin sodium methanesulfonate; | ||
SMILES | CCC(C)CCCCC(=O)NC(CCNCS(=O)(=O)[O-])C(=O)NC(C(C)O)C(=O)NC(CCNCS(=O)(=O)[O-])C(=O)NC1CCNC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC(=O)C(NC1=O)CCNCS(=O)(=O)[O-])CC(C)C)CC(C)C)CCNCS(=O)(=O)[O-])CCNCS(=O)( | ||
Chemical Name | |||
Formula | C58H105N16Na5O28S5 | M. Wt | 1749.81 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Colistimethate is a broad-spectrum polymyxin antibiotic against most aerobic Gram-negative bacteria except Proteus bacteria. Colistimethate is a mixture of methanesulfonate derivatives of cyclic polypeptides colistin A and B from Bacillus colistinus or B. polymyxa. Colistin functions as a surfactant which penetrates into and disrupts the bacterial cell membrane, thereby resulting in bactericidal effect. |
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