LCI699 New
Data Sheet
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| CAS No. | 928134-65-0 | Cat. No. | BCP16339 |
| Name | LCI699 | ||
| Synonyms | LCI-699;LCI 699;Osilodrostat; | ||
| SMILES | C1CC2=CN=CN2C1C3=C(C=C(C=C3)C#N)F | ||
| Chemical Name | |||
| Formula | C13H10FN3 | M. Wt | 227.24 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Osilodrostat, also known as LCI699, is a potent inhibitor of 11β-hydroxylase, the enzyme which catalyzes the final step of cortisol synthesis. LCI699 may thus be a potential new treatment for all forms of Cushing's syndrome. Current evidence indicates that the novel aldosterone inhibitor LCI699 is an effective and well-tolerated antihypertensive agent that lowers plasma aldosterone concentration and produces a mild ACTH-stimulated cortisol response suppressive effect. | ||
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