Fiboflapon New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 936350-00-4 | Cat. No. | BCP30434 |
| Name | Fiboflapon | ||
| Synonyms | AM-803; AM 803; AM803; GSK2190915;GSK-2190915; GSK 2190915; | ||
| SMILES | CCOC1=NC=C(C=C1)C2=CC=C(C=C2)CN3C4=C(C=C(C=C4)OCC5=NC=C(C=C5)C)C(=C3CC(C)(C)C(=O)O)SC(C)(C)C | ||
| Chemical Name | |||
| Formula | C38H43N3O4S | M. Wt | 637.84 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Fiboflapon, also known as AM-803 and GSK2190915, is a potent, oral, once daily FLAP inhibitor (5-lipoxygenase-activating protein inhibitor). GSK2190915 attenuated the early (0-2 h) and late (4-10 h) asthmatic responses to inhaled allergen compared with placebo. GSK2190915 shows potential as a treatment for patients with asthma. Efficacy was demonstrated for GSK2190915 30 mg compared with placebo in day-time symptom scores and day-time SABA use. | ||
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