SCH 79797

  • Chemical Properties
CAS No. 245520-69-8 Cat. No. BCP21206
Name SCH 79797
Synonyms SCH-79797; SCH79797;
Formula C23H25N5 M. Wt 371.48
  • Biological Activity
Description SCH-79797 is a potent and selective PAR1 antagonist. SCH-79797 limits myocardial ischemia/reperfusion injury in rat hearts. SCH 79797 protects against ischemia/reperfusion-induced arrhythmias in the rat hearts. SCH 79797 and its N-methyl analog (SCH 203099) inhibited binding of a high-affinity thrombin receptor-activating peptide ([(3)H]haTRAP, Ala-Phe(p-F)-Arg-ChA-HArg-[(3)H]Tyr-NH(2)) to PAR-1 with IC(50) values of 70 and 45 nM, respectively.
Related Products 1216720-69-2(SCH 79797 dihydrochloride)
Pathways GPCR/G Protein 
Targets PAR 

Structure

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