SCH 79797
CAS No. | 245520-69-8 | Cat. No. | BCP21206 |
Name | SCH 79797 | ||
Synonyms | SCH-79797; SCH79797; | ||
Formula | C23H25N5 | M. Wt | 371.48 |
Description | SCH-79797 is a potent and selective PAR1 antagonist. SCH-79797 limits myocardial ischemia/reperfusion injury in rat hearts. SCH 79797 protects against ischemia/reperfusion-induced arrhythmias in the rat hearts. SCH 79797 and its N-methyl analog (SCH 203099) inhibited binding of a high-affinity thrombin receptor-activating peptide ([(3)H]haTRAP, Ala-Phe(p-F)-Arg-ChA-HArg-[(3)H]Tyr-NH(2)) to PAR-1 with IC(50) values of 70 and 45 nM, respectively. | ||
Related Products | 1216720-69-2(SCH 79797 dihydrochloride) | ||
Pathways | GPCR/G Protein | ||
Targets | PAR |
Structure
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