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CAS No. | 245520-69-8 | Cat. No. | BCP21206 |
Related Products | 1216720-69-2(SCH 79797 dihydrochloride) | ||
Name | SCH 79797 | ||
Synonyms | SCH-79797; SCH79797; | ||
SMILES | CC(C)C1=CC=C(C=C1)CN2C=CC3=C2C=CC4=C3C(=NC(=N4)NC5CC5)N | ||
Chemical Name | |||
Formula | C23H25N5 | M. Wt | 371.48 |
Purity | 98% | Storage | Store at 4-8°C |
Description | SCH-79797 is a potent and selective PAR1 antagonist. SCH-79797 limits myocardial ischemia/reperfusion injury in rat hearts. SCH 79797 protects against ischemia/reperfusion-induced arrhythmias in the rat hearts. SCH 79797 and its N-methyl analog (SCH 203099) inhibited binding of a high-affinity thrombin receptor-activating peptide ([(3)H]haTRAP, Ala-Phe(p-F)-Arg-ChA-HArg-[(3)H]Tyr-NH(2)) to PAR-1 with IC(50) values of 70 and 45 nM, respectively. |
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