MK-8033
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CAS No. | 1001917-37-8 | Cat. No. | BCP21388 |
Name | MK-8033 | ||
Synonyms | MK8033;MK 8033; | ||
SMILES | O=S(CC1=CC=C2C(C(C3=CC(C4=CN(C)N=C4)=CN=C3C=C2)=O)=C1)(NCC5=NC=CC=C5)=O | ||
Chemical Name | |||
Formula | C25H21N5O3S | M. Wt | 471.53 |
Purity | 98% | Storage | Store at 4-8°C |
Description | MK-8033 is a c-MET inhibitor in clinical trials. MK8033 is a selective small-molecule inhibitor, ATP competitive. Phase I investigation of the cMet inhibitor MK-8033 is ongoing. Plans include a trial of this agent in refractory colorectal cancer, with pre- and post-treatment biopsies to evaluate for relevant molecular signatures. |
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