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ARQ 621 Chemical Structure

ARQ 621

Data Sheet For research use only. Not for human use.
Cat. No. :BCP28395CAS No. :1095253-39-6Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1095253-39-6 Cat. No. BCP28395
Name ARQ 621
Synonyms ARQ621; ARQ-621;
SMILES
Chemical Name
Formula C28H24Cl2FN5O2 M. Wt 552.43
Purity 98% Storage Store at 4-8°C
Description ARQ-621 is an allosteric, potent and selective inhibitor of Eg5, a microtubule-based ATPase motor protein involved in cell division. Over-expression of Eg5 causes genomic instability and tumor formation in mice; therefore, Eg5 is a potential anti-cancer target. Preclinical data shows anti-tumor activity of ARQ 621 across a wide range of cell lines from human solid and hematological malignancies.
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