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MK-0731 Chemical Structure

MK-0731

Data Sheet For research use only. Not for human use.
Cat. No. :BCP30541CAS No. :845256-65-7Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 845256-65-7 Cat. No. BCP30541
Name MK-0731
Synonyms MK0731; MK 0731;ALR-3456;ALR3456;ALR 3456;
SMILES CN1CCC(C(C1)F)N(C)C(=O)N2CC(=CC2(CO)C3=CC=CC=C3)C4=C(C=CC(=C4)F)F
Chemical Name
Formula C25H28F3N3O2 M. Wt 459.51
Purity 98% Storage Store at 4-8°C
Description MK-0731 is a synthetic small molecule with potential antineoplastic activity. MK0731 selectively inhibits kinesin spindle protein (KSP), which may result in the inhibition of mitotic spindle assembly, induction of cell cycle arrest during the mitotic phase, and apoptosis in tumor cells that overexpress KSP.
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