ARRY-520
Data Sheet
For research use only. Not for human use.
Get Quotation Now Tel: 0086-17754423994 or orders@biochempartner.com
Real-Time Inquiry ×
* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
Inquiry Online
×
* Required Fields.
Please complete the form below and we will contact you shortly.
Bulk Inquiry
×
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 885060-09-3 | Cat. No. | BCP07442 |
| Name | ARRY-520 | ||
| Synonyms | ARRY520;ARRY 520; Filanesib; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C20H22F2N4O2S | M. Wt | 420.47 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | ARRY-520 is a synthetic, small molecule targeting the kinesin spindle protein (KSP) with potential antineoplastic activity. KSP inhibitor ARRY-520 specifically inhibits KSP (kinesin-5 or Eg5), resulting in activation of the spindle assembly checkpoint, induction of cell cycle arrest during the mitotic phase, and consequently cell death in tumor cells that are actively dividing. Because KSP is not involved in postmitotic processes, such as neuronal transport, this agent does not cause the peripheral neuropathy that is often associated with tubulin-targeting agents. KSP is an ATP-dependent microtubule motor protein that is essential for the formation of bipolar spindles and the proper segregation of sister chromatids during mitosis. | ||
In the process of purchasing and using Biochempartner products, you can consult us if you have any problems: orders@biochempartner.com. We will try our best to solve all your doubts.
Recommend Products
More >
Tags:ARRY-520 supplier,ARRY-520 purchase,ARRY-520 manufacturer,ARRY-520 distributor,ARRY-520 cost,ARRY-520 buy,ARRY-520 for sale