Volitinib
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CAS No. | 1313725-88-0 | Cat. No. | BCP15079 |
Name | Volitinib | ||
Synonyms | Savolitinib; HMPL 504; HMPL0-504; HMPL504; AZD 6094; AZD 6094; AZD-6094; | ||
SMILES | CC(C1=CN2C=CN=C2C=C1)N3C4=NC(=CN=C4N=N3)C5=CN(N=C5)C | ||
Chemical Name | |||
Formula | C17H15N9 | M. Wt | 345.36 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Savolitinib, also known as Volitinib, AZD6094 or HMPL-504, is an orally bioavailable inhibitor of the c-Met receptor tyrosine kinase with potential antineoplastic activity. Volitinib selectively binds to and inhibits the activation of c-Met in an ATP-competitive manner, and disrupts c-Met signal transduction pathways. This may result in cell growth inhibition in tumors that overexpress the c-Met protein. |
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