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Proteasome inhibitor I
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CAS No. | 158442-41-2 | Cat. No. | BCP09729 |
Name | Proteasome inhibitor I | ||
Synonyms | Z-Ile-Glu(OtBu)-Ala-Leu-aldehyde; | ||
SMILES | |||
Chemical Name | |||
Formula | C32H50N4O8 | M. Wt | 618.76 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Proteasome inhibitor; inhibits chymotrypsin-like activity of the proteasome. Causes dopaminergic cell death in vitro. Prevents activation of NF-κB in response to TNF-α and okadaic acid (Cat. No. 1136) by inhibiting IκB-α degradation. Also inhibits NO production by LPS-activated macrophages. |
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