AZD-9496
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CAS No. | 1639042-08-2 | Cat. No. | BCP19229 |
Name | AZD-9496 | ||
Synonyms | AZD 9496;AZD9496; | ||
SMILES | CC1CC2=C(C(N1CC(C)(C)F)C3=C(C=C(C=C3F)C=CC(=O)O)F)NC4=CC=CC=C24 | ||
Chemical Name | |||
Formula | C25H25F3N2O2 | M. Wt | 442.47 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Selective Estrogen Receptor Degrader AZD9496 is an orally available selective estrogen receptor degrader (SERD), with potential antineoplastic activity. Upon administration, SERD AZD9496 binds to the estrogen receptor (ER) and induces a conformational change that results in the degradation of the receptor. This prevents ER-mediated signaling and inhibits the growth and survival of ER-expressing cancer cells. |
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