LSZ-102
Data Sheet
For research use only. Not for human use.
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| CAS No. | 2135600-76-7 | Cat. No. | BCP29222 |
| Name | LSZ-102 | ||
| Synonyms | LSZ102; LSZ 102; SERD LSZ102; SERD LSZ-102; SERD LSZ 102; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C25H17F3O4S | M. Wt | 470.46 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | LSZ102 is a potent ERα antagonist and degrader. LSZ102 showed ERα degradation IC50 = 0.2 nM. LSZ102 demonstrated IC50 for MCF-7 cells = 1.7 nM. Upon administration of LSZ102, this agent binds to the ER and induces the degradation of the receptor. This prevents ER activation and ER-mediated signaling, and inhibits the growth and survival of ER-expressing cancer cells. | ||
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